Favorite Teams leagues are not included in Single-Season records. Records only remain for 10 seasons.
Single-Season Leaders (Strikeouts)
Average
OBP
SLG
OPS
At Bats
Runs
Hits
Doubles
Triples
Homers
RBIs
Walks
Strikeouts
Stolen Bases
Caught Stealing
Sac Hits
Sac Fly
HBP
GIDP
D+/-
Wins
Losses
ERA
WHIP
Innings
Hits Allowed
HR Allowed
Walks (P)
Strikeouts (p)
Complete Games
Saves
Blown Saves
Shutouts
Quality Starts
Wild Pitches
Hit Batters
H/9
BB/9
SO/9
| 1. | Hader, Josh | (mattholland1975) | West Michigan Whitecaps | 373 |
| 2. | Kluber, Corey | (Mitch44) | Scarborough Red Storm | 372 |
| 3. | Cole, Gerrit | (Henny98) | Boston Braves | 364 |
| 4. | Kluber, Corey | (dzach) | Linndale Bills | 360 |
| 5. | Scherzer, Max | (tbsmit) | Hawaii Eruptions | 360 |
| 6. | Verlander, Justin | Miami Arachnids | 356 | |
| 7. | Scherzer, Max | (littlereb) | Texas Broncos | 350 |
| 8. | Scherzer, Max | (letsplaytwo) | Chicago Black Sox | 350 |
| 9. | Cole, Gerrit | (Trashfactory) | Haven Village Spartans | 350 |
| 10. | Scherzer, Max | (twsmee) | Fairview Township Strike | 350 |
| 11. | Verlander, Justin | (yankeebb) | Strange Things | 350 |
| 12. | Verlander, Justin | (malael) | New York Highlanders | 348 |
| 13. | deGrom, Jacob | (moosejaa) | Stockton Stars | 347 |
| 14. | Scherzer, Max | (dynasty) | New York Hammers | 347 |
| 15. | Corbin, Patrick | (filler) | Emerald Bay Energizers | 347 |
| 16. | deGrom, Jacob | (ColinBoucher) | Sycamore Street MollyWhoppers | 347 |
| 17. | Scherzer, Max | (gibblets1973) | Los Gibbletos 11leven | 347 |
| 18. | Scherzer, Max | (Gaberino) | HB Ballers | 347 |
| 19. | Verlander, Justin | (LorenzoCain) | New York Mets | 346 |
| 20. | Scherzer, Max | (garveyismypadre) | I'm Your Daddy🦎 | 346 |
| 21. | Kluber, Corey | (mattholland1975) | Durango Drunk Cowboys | 346 |
| 22. | Scherzer, Max | Poetic Force | 346 | |
| 23. | Cole, Gerrit | Gabon Black Panthers | 345 | |
| 24. | Sale, Chris | (Mayhem99) | Saint Charles RiverCats | 345 |
| 25. | Sale, Chris | (Bigredmachine90) | Barboursville Bacon | 345 |
| 26. | Scherzer, Max | (Johncitd) | Spring Sharks | 343 |
| 27. | Verlander, Justin | Los Angeles Rhinos | 343 | |
| 28. | Kluber, Corey | (dzach) | Linndale Bills | 343 |
| 29. | Kershaw, Clayton | (Trulaia) | Scranton Ducks | 342 |
| 30. | Sale, Chris | (YS) | Uranus Rebel Yells | 342 |
| 31. | deGrom, Jacob | (htennis) | What If I Never Get Over You | 341 |
| 32. | Scherzer, Max | (chunkyschumps) | New York Looters | 341 |
| 33. | Kluber, Corey | (Mitch44) | Scarborough Red Storm | 340 |
| 34. | Cole, Gerrit | (gdavis32) | Los Angeles Greats | 340 |
| 35. | Kluber, Corey | (mimadiga) | Virginia Athletics | 340 |
| 36. | Scherzer, Max | (jim2miller) | Alaska Sasquatch | 339 |
| 37. | Scherzer, Max | (Wheelski) | Los Angeles Dodgers | 339 |
| 38. | Scherzer, Max | (bryanreynolds) | Pittsburgh Rocket jet | 339 |
| 39. | Scherzer, Max | (rreebe916) | Kennebec Valley Jammers | 338 |
| 40. | Cole, Gerrit | South Africa Springboks | 338 | |
| 41. | Cole, Gerrit | (htennis) | The 100 Bellarkes | 338 |
| 42. | Sale, Chris | (sillymonkey) | Portland Punishers | 337 |
| 43. | Cole, Gerrit | (BigRedMachine90) | Huntington Panty Droppers | 337 |
| 44. | Scherzer, Max | Dartmouth BaseDogs | 337 | |
| 45. | Scherzer, Max | Dartmouth BaseDogs | 337 | |
| 46. | Scherzer, Max | (paranoid) | Las Vegas Chaos II | 336 |
| 47. | Verlander, Justin | (Bluesig) | Oroquieta Oliphaunts | 336 |
| 48. | Verlander, Justin | (dynasty) | Deer-Headed Wreaths | 336 |
| 49. | Scherzer, Max | (Trulaia) | Point Defiance Tiger | 336 |
| 50. | Scherzer, Max | Utica Post 229 | 336 |