Favorite Teams leagues are not included in Single-Season records. Records only remain for 10 seasons.
Single-Season Leaders (Strikeouts)
Average
OBP
SLG
OPS
At Bats
Runs
Hits
Doubles
Triples
Homers
RBIs
Walks
Strikeouts
Stolen Bases
Caught Stealing
Sac Hits
Sac Fly
HBP
GIDP
D+/-
Wins
Losses
ERA
WHIP
Innings
Hits Allowed
HR Allowed
Walks (P)
Strikeouts (p)
Complete Games
Saves
Blown Saves
Shutouts
Quality Starts
Wild Pitches
Hit Batters
H/9
BB/9
SO/9
| 1. | Hader, Josh | (mattholland1975) | West Michigan Whitecaps | 373 |
| 2. | Cole, Gerrit | Erie Spartans | 364 | |
| 3. | Verlander, Justin | Miami Arachnids | 356 | |
| 4. | Scherzer, Max | Fairview Township Strike | 350 | |
| 5. | Cole, Gerrit | (Trashfactory) | Haven Village Spartans | 350 |
| 6. | Verlander, Justin | (yankeebb) | Strange Things | 350 |
| 7. | deGrom, Jacob | (ColinBoucher) | Sycamore Street MollyWhoppers | 347 |
| 8. | deGrom, Jacob | (moosejaa) | Stockton Stars | 347 |
| 9. | Scherzer, Max | Wind City Challengers | 347 | |
| 10. | Corbin, Patrick | Belfast Giants | 347 | |
| 11. | Bieber, Shane | New York Mets | 347 | |
| 12. | Scherzer, Max | (gibblets1973) | Holyrood Purple H's | 347 |
| 13. | Scherzer, Max | (Sidneypointers) | Sidney Water Spaniels | 346 |
| 14. | Verlander, Justin | (mmeler) | New York Mets | 346 |
| 15. | Sale, Chris | (Bigredmachine90) | Barboursville Bacon | 345 |
| 16. | Sale, Chris | (befulton) | Saint Charles RiverCats | 345 |
| 17. | Cole, Gerrit | Reno High Towers | 345 | |
| 18. | Verlander, Justin | Tucson Toros | 343 | |
| 19. | Scherzer, Max | Ladson Cougars | 343 | |
| 20. | Scherzer, Max | (Schvitz) | Spring Heat | 343 |
| 21. | Sale, Chris | (YS) | Uranus Rebel Yells | 342 |
| 22. | Kershaw, Clayton | (Trulaia) | Scranton Ducks | 342 |
| 23. | deGrom, Jacob | (RcoRly) | What If I Never Get Over You | 341 |
| 24. | Cole, Gerrit | (coachmcs) | The Mandalorian Baby Yodas | 340 |
| 25. | Kluber, Corey | (Mitch44) | Scarborough Red Storm | 340 |
| 26. | Scherzer, Max | (Gradster10) | Cincinatti Rillas | 339 |
| 27. | Scherzer, Max | Polus Crewposters | 339 | |
| 28. | Scherzer, Max | (jim2miller) | Alaska Sasquatch | 339 |
| 29. | Cole, Gerrit | (Dark) | Jersey City Tom-Fooleries | 338 |
| 30. | Cole, Gerrit | (griffeyga) | The 100 Bellarkes | 338 |
| 31. | Scherzer, Max | (coachmcs) | Kennebec Valley Jammers | 338 |
| 32. | Scherzer, Max | (GaK54aGaM) | Dartmouth BaseDogs | 337 |
| 33. | Scherzer, Max | (paranoid) | Las Vegas Chaos II | 336 |
| 34. | Verlander, Justin | (Bluesig) | Oroquieta Oliphaunts | 336 |
| 35. | Verlander, Justin | (Gurg33) | Everyday Workers | 336 |
| 36. | Scherzer, Max | Utica Post 229 | 336 | |
| 37. | Cole, Gerrit | (mattyi4) | H-Town Fords | 335 |
| 38. | Cole, Gerrit | (Loum517) | Brooklin Cobras | 335 |
| 39. | Cole, Gerrit | (Eephus) | Oakmont Horns | 335 |
| 40. | Bauer, Trevor | (letsplaytwo) | San Francisco Giants | 335 |
| 41. | Strasburg, Stephen | (Strider99) | Philadelphia Wyverns | 335 |
| 42. | Scherzer, Max | (cubsfan44) | East Coast Screwballs | 334 |
| 43. | Scherzer, Max | Western Mustangs | 334 | |
| 44. | Martinez, Pedro | Eagle Creek Patriots | 334 | |
| 45. | Scherzer, Max | Big City Greens | 334 | |
| 46. | Cole, Gerrit | (Rosilver) | Freehold Yankees | 333 |
| 47. | Sale, Chris | (Bluesig) | Villaviciosa Blue Bears | 333 |
| 48. | Scherzer, Max | (joemcg) | OC Gators | 333 |
| 49. | Sale, Chris | (michelb3514) | Iowa Corn Pickers | 333 |
| 50. | Strasburg, Stephen | (Strider99) | Philadelphia Wyverns | 333 |